Cardiac Markers
Every cardiac markers calculator on CalcEngines — unit converters, derived indices and interpretive tools, each with its formula, a worked example and the reference intervals it is judged against.
19 calculators in this section
- BNP Unit ConverterConvert BNP between pg/mL, ng/L and pmol/L, and see why BNP and NT-proBNP are different molecules that cannot be read against each other's thresholds.
- CK-MB Activity Unit ConverterConvert CK-MB catalytic activity between U/L and µkat/L. First, the thing that goes wrong most often: CK-MB activity and CK-MB mass are different measurements, and a result in U/L cannot be read against a threshold in ng/mL.
- CK-MB Index CalculatorThe CK-MB relative index — CK-MB mass divided by total CK. Read it knowing that CK-MB is no longer the test for diagnosing a myocardial infarction, and that the index answers a narrower question: is this CK-MB coming from heart or from skeletal muscle?
- CK-MB Mass Unit ConverterConvert CK-MB mass between ng/mL, µg/L and mg/L — the first two are the same number. The reason this page is separate from the activity one is that CK-MB mass and CK-MB activity are different measurands with different units and different reference intervals, and there is no factor between them.
- GDF-15 Unit ConverterConvert growth differentiation factor 15 between pg/mL, ng/L and ng/mL — the first two are the same number. What the converted figure is worth is the harder question: GDF-15 predicts outcome about as well as any single biomarker in cardiology and diagnoses nothing at all, because almost everything raises it.
- GRACE ACS Risk Score CalculatorScore all eight GRACE variables from the admission observations and see the registry's own in-hospital risk band, with the distance from the ESC's 140-point early-invasive threshold.
- HEART Score CalculatorRisk-stratify chest pain in the emergency department from history, ECG, age, risk factors and troponin.
- High-Sensitivity Troponin Delta CalculatorCalculate the percentage change between two hs-troponin results, and see why guidelines define a significant delta by absolute change, not percentage.
- hs-CRP Cardiovascular Risk CalculatorClassify cardiovascular risk from high-sensitivity CRP using the AHA/CDC categories, and see when the result is not interpretable at all.
- hs-Troponin 0/1-Hour Algorithm InterpreterApply the ESC 0 h/1 h algorithm to a baseline and one-hour high-sensitivity troponin, using the thresholds published for your own assay. It sorts patients into rule-out, rule-in and observe — it does not diagnose, and it never overrides clinical judgement.
- Modified Sgarbossa Criteria CalculatorScore an ECG with left bundle branch block or a ventricular paced rhythm on both rules at once — the original weighted Sgarbossa criteria and the Smith modification, which replaces the fixed 5 mm threshold with a proportional ST/S ratio. Specific but not sensitive: a negative result does not exclude infarction.
- Myocardial Injury vs Infarction InterpreterA raised troponin is myocardial injury. Infarction needs acute injury plus evidence of ischaemia — and then a category. Built on the Fifth Universal Definition of Myocardial Infarction (2026), which replaced types 1 to 5 with primary, secondary and procedure-related.
- Myoglobin Unit ConverterConvert myoglobin between µg/L, ng/mL, mg/L and nmol/L. Myoglobin is the first marker to rise after myocardial injury and the least specific — skeletal muscle, rhabdomyolysis and poor renal clearance all raise it.
- NT-proBNP Heart Failure InterpreterRead an NT-proBNP against the right threshold for the setting and the patient's age: 300 pg/mL to rule out acute heart failure, 450, 900 or 1,800 to rule it in, and 125 in the outpatient clinic. Obesity lowers the number; kidney disease and atrial fibrillation raise it.
- NT-proBNP Unit ConverterConvert NT-proBNP between pg/mL, ng/L and pmol/L, with age-stratified thresholds and why it is the marker to trend on sacubitril/valsartan.
- TIMI Risk Score Calculator (NSTEMI/UA)Risk-stratify unstable angina and NSTEMI from seven bedside items, and see why GRACE has largely superseded it for formal risk stratification.
- Troponin I Unit Converter0.04 ng/mL and 40 ng/L are the same result. Convert cardiac troponin I between ng/L, pg/mL, ng/mL and µg/L — and see why no single cut-off can be printed on this page.
- Troponin in Renal Impairment InterpreterA chronically raised troponin in chronic kidney disease is real myocardial injury, not assay interference, and it carries real prognostic weight. The serial change identifies an acute event; the absolute value does not. Enter your own assay's 99th percentile.
- Troponin T Unit Converter0.014 ng/mL and 14 ng/L are the same number. Convert cardiac troponin T between ng/L, pg/mL, ng/mL and µg/L — and see why a mildly raised troponin T means something different from a mildly raised troponin I.