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Growth Differentiation Factor-15 (GDF-15) Unit Converter
Growth Differentiation Factor-15 (GDF-15) is a stress-responsive cytokine belonging to the transforming growth factor-β superfamily. It is released by numerous tissues, including the heart, kidneys, and placenta, in response to cellular stress, inflammation, and injury (such as ischemia and mitochondrial dysfunction).
Clinically, GDF-15 has emerged as a powerful, non-specific prognostic biomarker. Elevated levels correlate strongly with increased risk of all-cause mortality, cardiovascular disease (CVD) events, and progression of Chronic Kidney Disease (CKD). It provides valuable prognostic information beyond traditional risk factors like NT-proBNP and Troponin. This converter facilitates switching between the standard mass unit (pg/mL or ng/L) and the SI molar unit (pmol/L).
SI Units / Molar
RecommendedPicomoles per liter (Standard International).
Mass Equivalents
Clinical Context
Prognostic Thresholds (Approximate):
• Low Risk (Normal): < 1200 pg/mL
• Increased Mortality Risk: > 1800 pg/mL
GDF-15 is often measured in conjunction with cardiac biomarkers like Troponin and NT-proBNP to improve risk stratification in patients with heart failure or coronary artery disease. The conversion factor relies on MW 28,000 g/mol: 1 ng/mL ≈ 35.7 pmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., pg/mL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like pmol/L) are instantly updated.
Verify Units
Check the SI Units section. Note that 1 pg/mL is the same as 1 ng/L.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. 1 pg/mL is exactly equal to 1 ng/L.
The protein is released as a protective response to widespread cellular stress, making it an excellent indicator of overall biological risk and organ dysfunction.