IGF-1 (Insulin-like Growth Factor 1) Unit Converter

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Insulin-like Growth Factor 1 (IGF-1), also known as Somatomedin C, is a peptide hormone produced mainly by the liver in response to stimulation by **Human Growth Hormone (hGH)**. IGF-1 mediates most of the effects of hGH on bone and tissue growth (anabolism) and cell proliferation.

Clinically, measuring IGF-1 is the primary screening tool for disorders of hGH regulation, such as **Growth Hormone Deficiency (GHD)** and **Acromegaly** (excess hGH). Unlike hGH, which is released in rapid pulses, IGF-1 levels are stable throughout the day and reflect the average hGH secretion, making it a reliable diagnostic biomarker. This converter facilitates switching between the standard mass unit (ng/mL) and the International SI unit (nmol/L).

[Image of HPA axis regulation]

SI Units

Recommended

nmol/L

pmol/L

Nanomoles per liter (Standard International).

Conventional Units

ng/mL

µg/L

ng/dL

µg/dL

Clinical Context

Reference Range: IGF-1 levels are highly age-dependent, peaking during puberty (> 500 ng/mL) and declining steadily thereafter.

IGF-1 is used for both deficiency and excess diagnosis. In suspected Acromegaly, an elevated IGF-1 is the initial screening test. The conversion factor relies on MW 7,649 g/mol: 1 ng/mL ≈ 0.1307 nmol/L.

Clinical References

How to Use This Calculator

Follow these steps to get accurate clinical conversions instantly.

Enter Values

Input your laboratory results into the corresponding unit field (e.g., ng/mL). You can use either dot or comma decimals.

Automatic Conversion

The calculator works in real-time. As you type in one field, all other units (like nmol/L) are instantly updated.

Verify Units

Check the SI Units section. ng/mL and µg/L are numerically identical.

Reset

Use the Clear button to reset all fields before starting a new calculation.

? Frequently Asked Questions & Tips

Is ng/mL the same as µg/L?

Yes. 1 ng/mL is exactly equal to 1 µg/L.

Why is IGF-1 used over hGH?

IGF-1 levels are stable throughout the day, providing a more reliable indicator of average hGH activity than the pulsatile hGH measurement.

Disclaimer: This calculator is provided for educational and reference purposes only. It is not intended for clinical diagnosis, treatment, or medical decision-making. Always consult a qualified healthcare professional and refer to your laboratory’s official reference ranges before interpretation.

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