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IGFBP-3 Unit Converter
Insulin-like Growth Factor-Binding Protein 3 (IGFBP-3) is the most abundant of the six proteins that bind **IGF-1** (Insulin-like Growth Factor 1) in the circulation. Its primary function is to prolong the half-life of $\text{IGF-1}$ and modulate its activity by preventing it from immediately binding to its receptor.
Clinically, IGFBP-3 levels are used in conjunction with IGF-1 to diagnose **Growth Hormone Deficiency (GHD)**. Since approximately 80% of circulating IGF-1 is carried by IGFBP-3, this protein provides a stable, reliable reflection of the biological activity of hGH (Human Growth Hormone). Low levels strongly suggest GHD. This converter ensures accurate switching between the SI mass unit (mg/L) and the SI molar unit (nmol/L).
[Image of HPA axis regulation]SI Units
RecommendedMilligrams per liter or Nanomoles per liter.
Mass / Molar Equivalents
Clinical Context
Reference Range: Levels are highly age-dependent, but typically range from 3 – 5 mg/L (75 – 125 nmol/L) in young adults.
IGFBP-3 is used in conjunction with IGF-1 for better diagnostic accuracy in hGH disorders, as it is less affected by acute nutritional changes than IGF-1 alone. The molar conversion relies on MW 40,000 g/mol: 1 mg/L ≈ 25 nmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., mg/L). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. Conversions cover both mass (mg/L) and molar (nmol/L) units.
Verify Units
Check the SI Units section. mg/L is numerically identical to μg/mL.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. $1 \text{ mg/L}$ is exactly equal to $1 \mu\text{g/mL}$.
Testing $\text{IGFBP-3}$ increases the sensitivity of $\text{hGH}$ deficiency diagnosis, as its levels are more stable and directly reflect $\text{hGH}$ activity.