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NT-ProBNP Unit Converter
N-terminal pro b-type natriuretic peptide (NT-proBNP) is an inactive peptide released by the heart ventricles in response to pressure overload. It is a critical biomarker for the diagnosis and management of **Heart Failure (HF)**.
Clinically, elevated NT-proBNP levels help distinguish cardiac causes of dyspnea from non-cardiac causes. It has a longer half-life than BNP, making it a more stable marker. This converter facilitates switching between the standard mass units (pg/mL, ng/L) and the SI molar units (pmol/L).
Mass Units
CommonPicograms per milliliter (Numerically equivalent to ng/L).
SI / Molar Units
Clinical Context
Acute Heart Failure Cut-offs (Dyspnea):
• < 300 pg/mL: Heart failure is unlikely (Negative Predictive Value 98%).
• Age < 50 years: > 450 pg/mL suggests HF.
• Age 50 – 75 years: > 900 pg/mL suggests HF.
• Age > 75 years: > 1800 pg/mL suggests HF.
Conversion Logic:
The molecular weight of NT-proBNP is approximately 8457 Daltons (8.5 kDa).
1 pg/mL ≈ 0.1182 pmol/L.
1 pmol/L ≈ 8.46 pg/mL.
Clinical References
How to Use This Converter
Follow these steps to normalize NT-ProBNP values.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., pg/mL).
Automatic Conversion
The calculator converts between mass units and the SI molar unit (pmol/L).
Compare Context
Check the “Clinical Context” section to see age-adjusted cut-off values for heart failure diagnosis.
Reset
Use the Clear button to reset all fields.
Frequently Asked Questions
No. They are different molecules with different reference ranges. You cannot convert BNP values using this tool.
NT-proBNP naturally increases with age due to decreased renal clearance and physiological changes in the heart.