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N1-Methylnicotinamide Unit Converter

N1-Methylnicotinamide (N1-MN) is a major metabolite of Nicotinamide (Vitamin B3 or Niacin). It is formed in the liver by the enzyme Nicotinamide N-methyltransferase (NNMT) and is primarily excreted in the urine.

Clinically, urinary N1-Methylnicotinamide levels are the standard biomarker for assessing **Niacin status**. Low levels are indicative of Niacin deficiency (**Pellagra**), while elevated levels may be seen with high dietary intake or supplementation. Recently, it has also emerged as a potential biomarker for liver function and energy metabolism. This converter facilitates switching between the SI unit (µmol/L) and conventional mass units (mg/L, mg/dL).[Image of niacin metabolism pathway]

SI Units / Molar

Recommended

Micromoles per liter (Standard International).

Mass Equivalents

Clinical Context

Reference Values: Urinary excretion of N1-MN varies by diet, but deficiency is often defined as < 0.5 mg/day (or roughly < 0.5 mg/L in random urine depending on hydration).

In Pellagra, N1-MN is virtually absent from urine. The conversion factors are based on molecular weight (MW) 137.15 g/mol:
Mass to Molar: 1 mg/L ≈ 7.29 µmol/L
1 mg/dL ≈ 72.91 µmol/L.

Clinical References

How to Use This Converter

Follow these steps to get accurate concentration conversions instantly.

1

Enter Values

Input your laboratory results into the corresponding unit field (e.g., mg/L). You can use either dot or comma decimals.

2

Automatic Conversion

The calculator works in real-time. Conversions cover mass (mg/L) and molar (µmol/L) units.

3

Verify Units

Check the SI Units section. µmol/L is the standard for metabolic research.

4

Reset

Use the Clear button to reset all fields before starting a new calculation.

? Frequently Asked Questions & Tips
Is mg/L the same as µg/mL?

Yes. 1 mg/L = 1 µg/mL.

Why measure this metabolite?

It provides a more stable and direct index of Niacin (B3) nutritional status than measuring the vitamin itself in blood.

Disclaimer: This calculator is provided for educational and reference purposes only. It is not intended for clinical diagnosis, treatment, or medical decision-making. Always consult a qualified healthcare professional and refer to your laboratory’s official reference ranges before interpretation.