Child-Pugh Score Calculator

Child-Pugh Score Calculator

Grade the severity of chronic liver disease from bilirubin, albumin, INR, ascites and encephalopathy, and read off the Child-Pugh class with its survival estimates.

Child-Pugh score

5 items → 5–15 points
8pointsExample

Bilirubin 2.4 mg/dL (2), albumin 3.1 g/dL (2), INR 1.4 (1), mild ascites (2), no encephalopathy (1)

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How the score is built

Child-Pugh = bilirubin + albumin + INR + ascites + encephalopathy
each item
scores 1, 2 or 3 points
total
5 to 15 points
class
A = 5–6, B = 7–9, C = 10–15

Worked example

Bilirubin 2.4 mg/dL (2), albumin 3.1 g/dL (2), INR 1.4 (1), mild ascites (2), no encephalopathy (1)
2 + 2 + 1 + 2 + 1 = 8 points
7–9 points → Class B
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Scoring

Parameter1 point2 points3 points
Total bilirubin< 2 mg/dL2 – 3 mg/dL> 3 mg/dL
Serum albumin> 3.5 g/dL2.8 – 3.5 g/dL< 2.8 g/dL
INR< 1.71.7 – 2.3> 2.3
AscitesNoneMild / diuretic-responsiveModerate–severe / refractory
EncephalopathyNoneGrade I–IIGrade III–IV
In primary biliary cholangitis the bilirubin thresholds are conventionally raised to 10 mg/dL.

Classes and outcome

ClassPoints1-year survival2-year survival
A — well compensated5 – 6≈ 100%≈ 85%
B — significant compromise7 – 9≈ 81%≈ 57%
C — decompensated10 – 15≈ 45%≈ 35%
Survival figures are from the original validation cohorts and predate modern management; treat them as relative rather than absolute risk.

How the score is used

Child-Pugh began as a way to predict who would survive portosystemic shunt surgery and became the standard shorthand for describing how decompensated a cirrhotic liver is. Two of its five items are clinical judgements rather than measurements, which is both its weakness — ascites and encephalopathy grading vary between observers — and the reason it captures something a purely biochemical score misses.

In transplant allocation it has largely been replaced by MELD and MELD-Na, which are continuous, objective and better calibrated to short-term mortality. Child-Pugh survives in everyday use because it still governs a great deal of practical decision-making: drug licensing and dose adjustment are written in terms of Child-Pugh class, as are many surgical risk assessments and the eligibility criteria for hepatocellular carcinoma treatments.

A few practical points affect the score in ways that are easy to miss. Albumin falls in any inflammatory or nephrotic state, so a low value is not always hepatic synthetic failure. INR is affected by warfarin and by direct oral anticoagulants, which makes the score unreliable in an anticoagulated patient — MELD-XI exists for exactly that reason. Ascites should be graded on the current clinical state rather than the worst it has ever been, since a patient controlled on diuretics scores two points, not three.

Recalculate after any change in treatment or clinical state. Child-Pugh describes a moment, not a fixed prognosis, and a patient who stops drinking or clears a viral infection can move a full class within months.

Frequently asked questions

What is the difference between Child-Pugh and MELD?

Child-Pugh grades severity into three classes using five items, two of them subjective. MELD is a continuous score computed from bilirubin, creatinine, INR and sodium, designed to predict 90-day mortality, and is what most transplant programmes use for allocation. Child-Pugh remains the standard for drug dosing and surgical risk.

Which bilirubin units does the score use?

The classic thresholds are in mg/dL. In SI units they correspond to roughly under 34 µmol/L, 34–51 µmol/L and over 51 µmol/L.

Can Child-Pugh class improve?

Yes. Alcohol abstinence, viral suppression, diuresis and nutritional support can all move a patient from class C to B or B to A, and the score should be recalculated after any change in clinical state rather than treated as fixed.

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References

  1. Pugh RNH, Murray-Lyon IM, Dawson JL, et al. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973;60(8):646–9.
  2. Child CG, Turcotte JG. Surgery and portal hypertension. In: The Liver and Portal Hypertension. 1964:50–64.

Not medical advice. For healthcare professionals and education. Reference intervals vary by laboratory and assay — always use your own laboratory's. Never base a dose or a treatment decision on this page alone. Full disclaimer at calcengines.com/disclaimer/