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Osteocalcin (OCN) Unit Converter
Osteocalcin (OCN), also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a non-collagenous protein secreted by osteoblasts. It is a specific clinical marker of **bone formation** (bone turnover).
Clinically, serum Osteocalcin levels are used to assess bone turnover in osteoporosis, Paget’s disease, and primary hyperparathyroidism. This expanded converter facilitates switching between all common mass units (ng/mL, μg/L, μg/dL) and SI molar units (nmol/L, pmol/L).
Standard Reporting
Most CommonIntact Osteocalcin (1-49) MW ≈ 5800 Da.
Extended Equivalents
Clinical Context
Clinical Significance:
• Elevated levels: High bone turnover (e.g., primary hyperparathyroidism, hyperthyroidism, Paget’s disease, high-turnover osteoporosis).
• Decreased levels: Hypoparathyroidism, hypothyroidism, cortisol excess (Cushing’s).
Conversion Logic:
The molecular weight of intact Osteocalcin (1-49) is approximately 5.8 kDa (5800 g/mol).
1 ng/mL = 1 μg/L.
1 ng/mL = 0.1 μg/dL.
1 ng/mL ≈ 0.1724 nmol/L.
Clinical References
How to Use This Converter
Follow these steps to normalize Osteocalcin values.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., ng/mL).
Automatic Conversion
The calculator converts between mass units and the SI molar unit (nmol/L).
Reset
Use the Clear button to reset all fields.
Frequently Asked Questions
It is a useful marker of bone formation. However, P1NP (Procollagen type I N-propeptide) and CTX (C-telopeptide) are currently the preferred reference markers for bone formation and resorption, respectively.
Yes. Osteocalcin is unstable. Serum or plasma samples must be handled carefully (kept cold) to prevent degradation, which can lower results.