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Alpha-1-Acid Glycoprotein Unit Converter
Alpha-1-Acid Glycoprotein (AAG), also known as orosomucoid, is an acute-phase protein synthesized primarily in the liver. It accounts for approximately 1-3% of plasma proteins and is characterized by a very high carbohydrate content (45%) and a low pI (2.7–3.5).[Image of acute phase protein response]
Functionally, AAG acts as a carrier protein for basic and lipophilic compounds, including steroid hormones and drugs like propranolol, lidocaine, and methadone. Unlike albumin (which binds acidic drugs), elevated AAG levels can significantly decrease the free (active) fraction of basic drugs, altering their pharmacokinetics. Clinically, it is a slow-reacting positive acute-phase reactant, rising in response to systemic inflammation, infection, and trauma. This converter facilitates accurate switching between the standard international unit (g/L) and conventional units like mg/dL.
SI Units
RecommendedGrams per liter (Standard International).
Conventional Units
*Molar conversion is approximate (based on MW ≈ 41 kDa).
Clinical Context
AAG levels increase 2-4 fold during acute inflammation, typically peaking 3-5 days after the insult (slower than CRP). Conditions associated with elevated AAG include myocardial infarction, autoimmune diseases (SLE, Crohn’s), and malignancy.
Decreased levels are seen in conditions involving protein loss (nephrotic syndrome, protein-losing enteropathy) or decreased synthesis (hepatic failure, malnutrition). Furthermore, estrogen (pregnancy or oral contraceptives) tends to lower AAG levels. Reference ranges are typically 50 – 120 mg/dL (0.5 – 1.2 g/L).
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., mg/dL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like g/L) are instantly updated.
Verify Units
Check the SI Units section for the internationally recommended reporting standard (g/L).
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
It is the older name for Alpha-1-Acid Glycoprotein. The terms are used interchangeably in medical literature.
While rare for AAG, molar units are sometimes used in research. We use a molecular weight of 41,000 Da for this calculation.