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Anti-TSHR Antibody Unit Converter
Anti-TSH Receptor Antibodies (Anti-TSHR), often referred to as TRAb (Thyrotropin Receptor Antibodies), are autoantibodies that bind directly to the TSH receptor on thyroid follicular cells. Depending on their function, they can either mimic TSH, stimulating the thyroid to produce excess hormone (causing Graves’ disease), or block TSH action, causing hypothyroidism.
Clinically, measuring Anti-TSHR is the gold standard for distinguishing Graves’ disease from other causes of thyrotoxicosis (like toxic nodular goiter or thyroiditis). It is also critical in pregnant women with a history of Graves’ disease, as these IgG antibodies can cross the placenta and cause neonatal thyrotoxicosis. Results are reported in International Units (IU/L or IU/mL) standardized against WHO reference preparations. This converter allows for easy switching between these volume-based reporting standards.
SI Units
RecommendedInternational Units per liter (Standard SI).
Conventional Units
Clinical Context
Anti-TSHR (TRAb) is positive in 90-100% of patients with active Graves’ disease. There are two specific types often mentioned: TSI (Thyroid Stimulating Immunoglobulin) and TBII (Thyrotropin-Binding Inhibitory Immunoglobulin). Most general TRAb assays measure both.
A level > 1.75 IU/L is typically considered positive (assay dependent). In patients undergoing treatment with antithyroid drugs, a decline in TRAb levels predicts the likelihood of remission. High levels in the third trimester of pregnancy indicate a high risk for fetal/neonatal hyperthyroidism.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., IU/L). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like IU/mL) are instantly updated.
Verify Units
Check the SI Units section. IU/L is the most common reporting unit for this assay.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes, for TSH receptor antibodies, “Units” and “International Units” are used interchangeably in clinical reports.
This test measures the activity/binding of a mixture of antibodies, not their physical weight.