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Medical Calculator

CYFRA 21-1 Unit Converter

CYFRA 21-1 is a soluble fragment of cytokeratin 19, a protein found in the epithelial cells of the lung, bladder, and cervix. Elevated serum levels indicate increased turnover or damage of these cells.

Clinically, CYFRA 21-1 is the most useful serological tumor marker for **Non-Small Cell Lung Cancer (NSCLC)**, particularly the squamous cell carcinoma subtype. It is used to monitor treatment response, detect early recurrence, and estimate prognosis. While high specificity is desirable, levels can also be raised by benign lung diseases (pneumonia, tuberculosis) and hepatic/renal failure. Results are reported in mass units (ng/mL or $\mu\text{g/L}$) or International Units (IU/mL). This converter allows seamless switching between these reporting standards.

SI Units

Recommended

Micrograms per liter or Nanograms per milliliter (Numerically equivalent).

Conventional Units

Clinical Context

Reference Range: In healthy individuals, CYFRA 21-1 is typically < 3.3 ng/mL ($\mu\text{g/L}$).

Levels exceeding $30 \text{ ng/mL}$ in high-risk patients are highly suggestive of NSCLC. For post-treatment monitoring, a rising trend is more significant than a single absolute value. The conversion factor is simple: $\mathbf{1 \text{ ng/mL} = 1 \mu\text{g/L}}$. Molar units are not applicable due to the marker’s fragmented nature.

Clinical References

How to Use This Calculator

Follow these steps to get accurate clinical conversions instantly.

1

Enter Values

Input your laboratory results into the corresponding unit field (e.g., ng/mL). You can use either dot or comma decimals.

2

Automatic Conversion

The calculator works in real-time. As you type in one field, all other units (like $\mu\text{g/L}$ or $\text{pg/mL}$) are instantly updated.

3

Verify Units

Check the SI Units section. $\mu\text{g/L}$ and $\text{ng/mL}$ are numerically equivalent and are the standard mass units.

4

Reset

Use the Clear button to reset all fields before starting a new calculation.

? Frequently Asked Questions & Tips
Is $\text{ng/mL}$ the same as $\mu\text{g/L}$?

Yes. They are numerically identical. $\text{ng/mL}$ is often used in the US, $\mu\text{g/L}$ internationally.

Why no molar units?

The marker is a fragmented protein, meaning the molecular weight is undefined and unusable for reliable molar conversion.

Disclaimer: This calculator is provided for educational and reference purposes only. It is not intended for clinical diagnosis, treatment, or medical decision-making. Always consult a qualified healthcare professional and refer to your laboratory’s official reference ranges before interpretation.