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S100B Protein Unit Converter
S100 Calcium-Binding Protein B (S100B) is an acidic calcium-binding protein concentrated in the central nervous system (glial cells) and also expressed in melanocytes.
Clinically, S100B is a valuable biomarker for **malignant melanoma** (reflecting tumor burden and metastases) and for assessing **brain injury** (e.g., concussion or stroke). This converter facilitates switching between standard mass units (μg/L, ng/L) and SI molar units (nmol/L), utilizing the standard dimer molecular weight.
Mass Units
StandardMicrograms per liter (Numerically equivalent to ng/mL).
SI / Molar Units
Clinical Context
Reference Values (Healthy): Typically < 0.10 μg/L (varies by assay).
Clinical Utility:
• Melanoma: Elevated levels correlate with advanced stage (Stage III/IV) and disease progression.
• Brain Injury: Used to screen low-risk head trauma patients to rule out the need for CT scans.
Conversion Logic:
Molecular Weight of S100B Dimer: ~21,000 Da (21 kDa).
1 μg/L ≈ 0.0476 nmol/L.
1 nmol/L ≈ 21 μg/L.
Clinical References
How to Use This Converter
Follow these steps to normalize S100B values.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., μg/L).
Automatic Conversion
The calculator converts between mass units and the SI molar unit (nmol/L).
Reset
Use the Clear button to reset all fields.
Frequently Asked Questions
Yes. 1 microgram per liter is numerically identical to 1 nanogram per milliliter.
S100B is released by melanoma cells. Increasing levels can indicate disease recurrence or progression even before symptoms appear.