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sFlt-1 Unit Converter
Soluble Fms-Like Tyrosine Kinase-1 (sFlt-1) is an anti-angiogenic protein produced by the placenta. It binds to pro-angiogenic factors like PlGF and VEGF, inhibiting their function.
Elevated levels of sFlt-1 are a hallmark of **Preeclampsia**. The ratio of **sFlt-1/PlGF** is a powerful predictor used to rule out preeclampsia in the short term. This converter facilitates switching between standard mass units (pg/mL, ng/mL) to ensure accurate ratio calculations.
Common Units
StandardPicograms per milliliter (Numerically equivalent to ng/L).
Higher Mass Units
Clinical Context
Reference Values: sFlt-1 levels normally rise slightly towards term but skyrocket in preeclampsia. Interpretation is almost always done via the ratio.
The sFlt-1/PlGF Ratio:
• < 38: Low risk (Rule-out preeclampsia for 1 week).
• > 38: Elevated risk.
• > 85 (Early onset) / > 110 (Late onset): Highly suggestive of preeclampsia/HELLP syndrome.
Conversion Logic:
1 pg/mL = 1 ng/L.
1 ng/mL = 1,000 pg/mL.
Clinical References
How to Use This Converter
Follow these steps to normalize sFlt-1 values.
Enter Values
Input your laboratory result into the corresponding unit field (e.g., pg/mL).
Automatic Conversion
The calculator instantly updates all other fields. Ensure units match your PlGF result before calculating the ratio.
Reset
Use the Clear button to reset all fields.
Frequently Asked Questions
Yes. 1 picogram per milliliter is numerically identical to 1 nanogram per liter.
sFlt-1 alone has wide biological variation. The ratio with PlGF standardizes the placental angiogenic imbalance, improving diagnostic accuracy.