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Troponin I (TnI) Unit Converter
Cardiac Troponin I (cTnI) is a highly specific biomarker for myocardial injury. Elevated levels are the gold standard for diagnosing acute myocardial infarction (heart attack).
The introduction of **High-Sensitivity Troponin (hs-cTnI)** assays has led to reporting in whole numbers (ng/L) rather than the decimals (ng/mL) used in conventional assays. This converter facilitates switching between Conventional and High-Sensitivity units to prevent interpretation errors.
Conventional Units
Older AssaysNanograms per milliliter. Typical cutoff ≈ 0.04.
High-Sensitivity
Nanograms per liter. Typical cutoff ≈ 14 – 26.
Clinical Context
Reference Values (Assay Dependent):
• Conventional (Generic): 99th percentile cutoff is often ~0.04 ng/mL.
• High-Sensitivity (hs-cTnI): Cutoffs are gender-specific and much lower, often ~10-30 ng/L.
Interpretation:
A rise and/or fall of cTn values with at least one value above the 99th percentile, in the clinical context of ischemia, indicates Acute Myocardial Infarction (AMI).
Conversion Logic:
1 ng/mL = 1,000 ng/L (pg/mL).
1 ng/L = 0.001 ng/mL.
Clinical References
How to Use This Converter
Follow these steps to normalize Troponin values.
Enter Values
Input your laboratory result into the corresponding unit field. Use ng/mL for older assays or ng/L for high-sensitivity.
Automatic Conversion
The calculator automatically multiplies or divides by 1000 to switch between units.
Reset
Use the Clear button to reset all fields.
Frequently Asked Questions
No. Troponin I and Troponin T are different proteins. They have different reference ranges and are not interchangeable, though both indicate heart damage.
It means the test can detect much lower levels of troponin (ng/L) than older tests (ng/mL), allowing for earlier detection of heart attacks.