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Acetaminophen Unit Converter
Acetaminophen (also known as paracetamol or N-acetyl-p-aminophenol) is a widely used analgesic and antipyretic agent. It acts primarily in the central nervous system by inhibiting the cyclooxygenase (COX) pathways, reducing pain and fever. Unlike NSAIDs, it lacks significant anti-inflammatory properties and does not affect platelet function.[Image of acetaminophen chemical structure and metabolism pathway]
Therapeutic serum concentrations typically range from 10–20 µg/mL (≈66–132 µmol/L). In cases of overdose, the liver’s conjugation pathways become saturated, leading to the accumulation of the toxic metabolite NAPQI (N-acetyl-p-benzoquinone imine). Levels exceeding 150 µg/mL at 4 hours post-ingestion may indicate hepatotoxicity and require antidotal therapy with N-acetylcysteine (NAC). This converter allows clinicians to seamlessly switch between µmol/L, µg/mL, mg/dL, and other common reporting units.
SI Units
RecommendedMicromoles per liter (Standard International).
Conventional Units
Clinical Context
Acetaminophen levels are monitored to confirm therapeutic compliance or evaluate potential toxicity after acute ingestion. The risk of hepatotoxicity is assessed using the Rumack-Matthew Nomogram, which correlates serum concentration with time elapsed since ingestion (valid between 4 and 24 hours).
A serum level of 150 µg/mL (990 µmol/L) or higher at 4 hours is the standard threshold for initiating treatment in the US to prevent liver failure. Accurate unit conversion is vital, as confusion between mg/dL and µg/mL can lead to potentially fatal errors in treatment decisions.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., µg/mL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like µmol/L or mg/dL) are instantly updated.
Verify Units
Check the SI Units section for the internationally recommended reporting standard (µmol/L).
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Generally, >150 µg/mL at 4 hours post-ingestion. Always consult the Rumack-Matthew nomogram.
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