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Acetoacetic Acid Unit Converter
Acetoacetic acid (Acetoacetate) is the first “ketone body” produced by the liver during fatty acid metabolism. It acts as a central intermediate that can be further converted into beta-hydroxybutyrate (the predominant ketone in severe ketoacidosis) or spontaneously decarboxylated into acetone.[Image of ketone body synthesis and breakdown]
Under normal physiological conditions, serum acetoacetate levels are very low. However, during periods of restricted carbohydrate intake, starvation, or insulin deficiency (as seen in Diabetic Ketoacidosis – DKA), levels rise significantly. While many point-of-care blood meters measure beta-hydroxybutyrate, the traditional nitroprusside urine dipstick reaction specifically detects acetoacetate. Accurate measurement and unit conversion are critical for diagnosing metabolic acidosis and monitoring recovery.
SI Units
RecommendedMillimoles per liter (Standard International).
Conventional Units
Clinical Context
Acetoacetate testing is primarily used to investigate metabolic acidosis. In Diabetic Ketoacidosis (DKA), the ratio of beta-hydroxybutyrate to acetoacetate typically rises (often > 3:1). However, during treatment, beta-hydroxybutyrate oxidizes back into acetoacetate.
This can cause a paradoxical “worsening” of the nitroprusside test (which only detects acetoacetate) even as the patient is clinically improving. Normal serum levels are typically < 1 mg/dL (< 0.1 mmol/L). Values significantly higher indicate a state of ketosis or ketoacidosis.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., mg/dL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like mmol/L) are instantly updated.
Verify Units
Check the SI Units section for the internationally recommended reporting standard (mmol/L).
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
No. This calculator is specific to Acetoacetate. Beta-Hydroxybutyrate has a different molecular weight (104.1 g/mol) and uses a separate converter.
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