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Digitoxin Unit Converter
Digitoxin is a cardiac glycoside historically used to treat heart failure and certain types of cardiac arrhythmias. It works by inhibiting the Na+/K+ ATPase pump, which increases intracellular calcium and enhances myocardial contractility. Digitoxin is characterized by its long half-life, meaning it accumulates over time.
Monitoring serum Digitoxin levels is essential for therapeutic drug monitoring (TDM) due to its narrow therapeutic index and potential for severe toxicity. This converter allows healthcare professionals to easily switch between conventional mass units (ng/mL, µg/L) and the International System of Units (SI) molar concentration (nmol/L).
Standard Units (SI/Mass)
PrimaryNanograms per milliliter or Nanomoles per liter.
Other Units
Clinical Context: Therapeutic Drug Monitoring
Therapeutic Range: Serum Digitoxin is monitored to maintain optimal therapeutic effects while avoiding toxicity. The typical therapeutic range is 9–30 ng/mL ≈ 12–40nmol/L.
Levels > 35 ng/mL are generally considered toxic, though toxicity can occur at lower levels depending on patient factors (e.g., electrolyte imbalances, renal function). Due to its exceptionally long half-life (around 7 days), stable steady-state levels can take weeks to achieve.
Conversion Factor: The conversion factor relies on the Molecular Weight of Digitoxin (MW = 764.95g/mol). 1ng/mL = 1µg/L ≈ 1.307 nmol/L
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Value
Input your laboratory result into the known unit field (e.g., ng/mL). You can use either dot or comma decimals.
View Conversion
The calculation runs automatically, converting the input to all other available units, including the SI standard nmol/L.
Verify Units
The ng/mL and µg/L values are always equal (1:1), which is a useful check for consistency.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. $1 \text{ ng/mL}$ is exactly equal to $1 \text{ µg/L}$.
Digitoxin has a narrow therapeutic index, meaning the dose needed for therapeutic effect is close to the dose that causes toxicity. TDM ensures safe and effective treatment.