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Hemoglobin Monomer (Hb Subunit) Unit Converter
Hemoglobin Monomer refers to a single globin chain (either α or β) which normally combines with three other chains to form the hemoglobin tetramer (HbA). These individual subunits are typically only measured in research settings or advanced clinical laboratories specializing in hemoglobinopathies.
In physiological conditions, free hemoglobin (mostly tetramers and dimers) is rapidly bound by Haptoglobin, and unpaired globin chains are degraded. Measurement of free chains may be relevant in conditions like thalassemia or sickle cell disease, where unstable chains precipitate and damage the red blood cell structure. The conversion relies on the approximate molecular weight of a single globin subunit (16,125 g/mol).
SI Units
RecommendedMicromoles or millimoles per liter (SI units).
Conventional Units
Clinical Context
Physiological Role: Measuring the concentration of free hemoglobin subunits in plasma is not a routine diagnostic test. Instead, clinicians usually measure the total amount of free hemoglobin in plasma (a sign of hemolysis) or assess Haptoglobin, which binds free hemoglobin.
In severe intravascular hemolysis, free hemoglobin (tetramers) is released, saturates haptoglobin, and begins to dissociate into dimers and monomers, contributing to potential kidney damage. The conversion factor relies on MW 16,125 g/mol: 1 mg/dL ≈ 0.62 µmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate research and reference conversions instantly.
Enter Values
Input your concentration into the corresponding unit field (e.g., mg/dL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like µmol/L and g/L) are instantly updated.
Verify Units
Check the SI Units section. µmol/L and mmol/L are convenient for comparing with other small proteins and peptides.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. 1 µg/mL is exactly equal to 1 mg/L.
This calculator treats the monomeric globin chain as the unit. Total Hgb measures the functional tetramer, which has four such subunits and a molecular weight about four times higher.