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Isoleucine (Ile) Unit Converter
Isoleucine (Ile) is one of the three essential Branched-Chain Amino Acids (BCAAs), alongside Leucine and Valine. It is crucial for muscle protein synthesis, tissue repair, and acts as a fuel source during exercise and fasting states.
Clinically, Isoleucine levels are measured as part of an amino acid analysis panel, primarily to screen for Maple Syrup Urine Disease (MSUD), a severe inherited metabolic disorder caused by the failure to break down BCAAs. Elevated Isoleucine (along with Leucine and Valine) is the diagnostic hallmark of MSUD, leading to neurotoxicity if untreated. This converter facilitates accurate switching between the conventional mass unit (mg/dL) and the International SI unit (µmol/L).
[Image of branched-chain amino acid metabolism pathway]SI Units
RecommendedMicromoles per liter (Standard International).
Conventional Units
Clinical Context
Reference Range (Fasting): Plasma Isoleucine levels are typically stable, ranging from 40–100 µmol/L.
In MSUD, Isoleucine levels can spike to over 1000 µmol/L. Monitoring these three BCAAs (Isoleucine, Leucine, Valine) is vital for management and dietary control in affected patients. The conversion factor relies on MW 131.17 g/mol: 1 mg/dL ≈ 76.24 µmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., mg/dL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like µmol/L) are instantly updated.
Verify Units
Check the SI Units section. µmol/L is the standard for amino acid analysis.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
The three essential Branched-Chain Amino Acids are Isoleucine, Leucine, and Valine.
Accurate conversion between mass and molar units is crucial for diagnosing MSUD, as treatment relies on tightly controlling BCAA concentrations.