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Lidocaine Unit Converter
Lidocaine (Xylocaine) is a common local anesthetic and, when administered intravenously, a Class Ib antiarrhythmic agent. It stabilizes the neuronal and myocardial cell membranes by inhibiting sodium ion influx, thus reducing electrical excitability. [Image of antiarrhythmic drug classification]
Lidocaine has a narrow therapeutic index, meaning the effective dose is close to the toxic dose. Therapeutic Drug Monitoring (TDM) is essential to maintain concentrations within the therapeutic window (1.5–5.0 µg/mL) while avoiding signs of toxicity, which include central nervous system (CNS) effects (paresthesia, drowsiness, seizures) and cardiotoxicity. This converter facilitates switching between the SI unit (µmol/L) and the conventional mass unit (µg/mL).
SI Units
RecommendedMicromoles per liter (Standard International).
Conventional Units
Clinical Context
Therapeutic Range: 1.5–5.0 µg/mL (6.4–21.3 µmol/L).
Toxicity often begins with minor CNS symptoms (> 5 µg/mL) and progresses to seizures and coma (> 10 µg/mL). Dosage must be adjusted in patients with congestive heart failure (CHF) or liver disease due to impaired clearance. The conversion factor relies on MW 234.34 g/mol: 1 µg/mL ≈ 4.267 µmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., µg/mL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like µmol/L and mg/L) are instantly updated.
Verify Units
Check the SI Units section. µg/mL is numerically identical to mg/L.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. 1 µg/mL is exactly equal to 1 mg/L.
It is essential due to the narrow therapeutic window. Too low, and the antiarrhythmic effect is lost; too high, and the patient risks severe CNS or cardiac toxicity.