Aldolase Unit Converter

Aldolase (specifically Aldolase A in muscle) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. It is found in high concentrations in skeletal muscle, the liver, and the brain.

Clinically, serum aldolase is a marker for muscle damage and hepatic injury. It is particularly useful in diagnosing and monitoring muscular dystrophy (such as Duchenne’s), polymyositis, and dermatomyositis. While Creatine Kinase (CK) is often the preferred muscle enzyme due to higher specificity, aldolase remains valuable when CK is normal or to differentiate between neurogenic (normal aldolase) and myopathic (elevated aldolase) muscle wasting. Because it is an enzyme, results are reported in units of activity (U/L or µkat/L).