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Biotin (Vitamin B7) Unit Converter
Biotin (Vitamin B7), formerly known as Vitamin H, is a water-soluble B-complex vitamin. It functions as an essential cofactor for five carboxylase enzymes that catalyze critical steps in the metabolism of fatty acids, glucose, and amino acids.[Image of biotin structure]
While frank biotin deficiency is rare, interest in biotin measurement has surged due to the popularity of high-dose supplements for hair and nail health. Crucially, high circulating levels of biotin can cause significant interference in laboratory immunoassays that utilize the streptavidin-biotin binding mechanism. This can lead to falsely low troponin (masking heart attacks) or falsely abnormal thyroid function tests. This converter allows clinicians to switch between the standard molar unit (nmol/L) and mass units (ng/mL, pg/mL) to assess potential interference thresholds.
SI Units
RecommendedNanomoles per liter (Standard International).
Conventional Units
Clinical Context
Normal plasma biotin levels in healthy individuals typically range from 0.2 – 3.0 nmol/L (approx. 50 – 730 pg/mL).
However, patients taking high-dose biotin (5-10 mg/day) can achieve serum levels > 100 ng/mL. Many immunoassay package inserts warn that interference may occur at biotin levels as low as 10 – 30 ng/mL. The conversion factor relies on the molecular weight of 244.31 g/mol: 1 nmol/L ≈ 0.244 ng/mL (or 1 ng/mL ≈ 4.09 nmol/L).
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., ng/mL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like nmol/L) are instantly updated.
Verify Units
Check the SI Units section. nmol/L is the standard scientific unit.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Yes. 1 pg/mL is exactly equal to 1 ng/L.
Usually only if lab results (like TSH or Troponin) do not match the clinical picture and the patient takes hair/nail supplements.