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Leucine (Leu) Unit Converter
Leucine (Leu) is one of the three Branched-Chain Amino Acids (BCAAs), which are essential and cannot be synthesized by the body. Leucine is considered the most critical BCAA for muscle protein synthesis due to its role in activating the mTOR signaling pathway.
Clinically, Leucine levels are measured in amino acid analysis, primarily for the diagnosis and monitoring of Maple Syrup Urine Disease (MSUD). In MSUD, the body cannot break down Leucine, Isoleucine, and Valine, leading to toxic accumulation of these amino acids and their ketoacids in the brain. High levels are toxic and require strict dietary restriction. This converter facilitates accurate switching between the conventional mass unit (mg/dL) and the International SI unit (µmol/L).
SI Units
RecommendedMicromoles per liter (Standard International).
Conventional Units
Clinical Context
Reference Range (Fasting): Plasma Leucine levels are typically stable, ranging from 60–160 µmol/L.
In acute decompensation of MSUD, Leucine levels can skyrocket (> 1000 µmol/L), leading to severe neurological symptoms, including cerebral edema. Monitoring Leucine is essential for therapeutic control. The conversion factor relies on MW 131.17 g/mol: 1 mg/dL ≈ 76.24 µmol/L.
Clinical References
How to Use This Calculator
Follow these steps to get accurate clinical conversions instantly.
Enter Values
Input your laboratory results into the corresponding unit field (e.g., mg/dL). You can use either dot or comma decimals.
Automatic Conversion
The calculator works in real-time. As you type in one field, all other units (like µmol/L) are instantly updated.
Verify Units
Check the SI Units section. µmol/L is the standard for amino acid analysis.
Reset
Use the Clear button to reset all fields before starting a new calculation.
Frequently Asked Questions & Tips
Leucine is considered the key BCAA for muscle building due to its ability to trigger the mTOR anabolic signaling pathway.
Plasma amino acid levels fluctuate after meals, so fasting is crucial for accurate baseline diagnostic readings.